Protease Activated Receptor (PAR)

カタログ番号	製品名	別名	ターゲット
T38836L	Protease-Activated Receptor-1, PAR-1 Agonist acetate		Protease-activated Receptor
	Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and whi...		Protease-activated Receptor
T38836	Protease-Activated Receptor-1, PAR-1 Agonist
	Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activatio...
T36288	Protease-Activated Receptor-1, PAR-1 Agonist TFA
	Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the ac...
T36289	Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
	Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1].
TP1046	SLIGRL-NH2	Protease-Activated Receptor-2 Activating Peptide	Protease-activated Receptor
	SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus.		Protease-activated Receptor
T36286	Protease-Activated Receptor-3 (PAR-3) (1-6), human
	TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.
T1986L	Atopaxar Hydrobromide		Protease-activated Receptor
	Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.		Protease-activated Receptor
T1986	Atopaxar	E5555,ER-172594-00	Protease-activated Receptor
	Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.		Protease-activated Receptor
TP1046L	PAR-2 Activating Peptide acetate	SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate	Protease-activated Receptor
	PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).		Protease-activated Receptor
T7137	I-191		Protease-activated Receptor
	I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.		Protease-activated Receptor
TQ0012	AZ3451		Protease-activated Receptor
	AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).		Protease-activated Receptor
TP1065	PAR-4 Agonist Peptide, amide TFA	PAR-4-AP (TFA),AY-NH2 (TFA)	Protease-activated Receptor
	PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited b...		Protease-activated Receptor
T7623	PAR-4 Agonist Peptide, amide	AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP	Protease-activated Receptor
	PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4).		Protease-activated Receptor
T7625	TRAP-6	PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)	Protease-activated Receptor
	TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).		Protease-activated Receptor
T1893	Parmodulin 2	ML 161	Protease-activated Receptor
	Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...		Protease-activated Receptor
T7513	Protease-Activated Receptor-2, amide	SLIGKV-NH2	Protease-activated Receptor
	Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M)		Protease-activated Receptor
T2370	AC-55541	AOB2796	Proteasome , Protease-activated Receptor
	AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.		Proteasome , Protease-activated Receptor
T8917	PAR-2-IN-1	IUN76750	Protease-activated Receptor
	PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.		Protease-activated Receptor
T7013	Vorapaxar	SCH 530348,MK-5348	Protease-activated Receptor
	Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).		Protease-activated Receptor
T12870	SCH79797 dihydrochloride		Apoptosis , Others , Protease-activated Receptor
	SCH79797 dihydrochloride is a selective antagonist of nonpeptide protease activated receptor 1 (PAR1).		Apoptosis , Others , Protease-activated Receptor
T3098	Vorapaxar sulfate	SCH 530348 sulfate,Zontivity,vorapaxar monosulfate	Protease-activated Receptor
	Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.		Protease-activated Receptor
T7380	Protease-Activated Receptor-4		Protease-activated Receptor
	Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy		Protease-activated Receptor
T4186	AC-264613	AC264613	Protease-activated Receptor
	AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha...		Protease-activated Receptor
T7573	TFLLR-NH2	TFLLR-NH2(2TFA)	Protease-activated Receptor
	TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).		Protease-activated Receptor
T7496	Thrombin Receptor Activator for Peptide 5 (TRAP-5)	Thrombin Receptor Activator for Peptide	Protease-activated Receptor
	Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in coronary heart disease (CHD) research.		Protease-activated Receptor
T63966	BMS-986141	UDM-003183	Protease-activated Receptor
	BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614 exhibits significant antithrombotic effects.		Protease-activated Receptor
T75902	SLIGRL-NH2 TFA	Protease-Activated Receptor-2 Activating Peptide TFA
	SLIGRL-NH2 TFA, also known as Protease-Activated Receptor-2 Activating Peptide TFA, is a Protease-Activated Receptor-2 (PAR-2) agonist [1].
T62507	Protease-Activated Receptor-1 antagonist 1
	Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor 1 (PAR-1) antagonist with an IC50 of 3 nM obtained by the FLIPR technique. antagonist 1 can be used to study thrombotic cardiovasc...
T80111	TRAP-5 amide
	TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1].
T64285	Protease-Activated Receptor-1 antagonist 2
	Protease-Activated Receptor-1 antagonist 2 is a selective, orally active protease-activated receptor-1 (PAR-1) antagonist (IC50: 7 nM). It has shown good pharmacokinetic properties and can be used for studies related to ...
T75904	PAR 4 (1-6) (TFA)
	PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4. This fragment of PAR 4 [1] exhibits targeted activation properties.
T74266	Protease-Activated Receptor-1 antagonist 2
	Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic character...
T80234	SFNGGP-NH2
	SFNGGP-NH2 is a biologically active peptide that interacts with Protease-Activated Receptor 3 (PAR-3), a high-affinity thrombin receptor. Human cutaneous mast cells express PAR-3 mRNA, implicating a role in itch mechanot...
T80240	Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
	Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype of G-protein coupled receptors involved in mediating thrombin...
T35955	PAR2 (1-6) amide (human) (trifluoroacetate salt)	PAR2 (1-6) amide (human) (trifluoroacetate salt)
	PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-lengt...
T36717	RWJ-56110 dihydrochloride
	RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits...